BIOINTEGRATION RESEARCH LAB
(BIRL)

Fabrication of hydrogel injectable filler for breast reconstruction

An increasing number of soft tissue filler substances have been introduced to reconstructive and purpose. In breast reconstruction surgery, after implantation of the implant, excessive formation of the capsule around the implant causes the formation of the spherical shape due to the hardening of the tissue. To solve this problems, our research team is developing synthesized copolymer hydrogel using biopolymer for breast reconstruction.

Development of a biodegradable biomimetic bone Plate/Screw and graft

We evaluate the efficacy and safty of biodegradable biomimetic bone plate/screw and graft.

Advantages of biodegradable biomimetic plate/screw and graft

- has an excellent osteoinductivity

- do not required a second surgery for removal

- allows space for new bone formation

- has good biocompatibility

Analysis: bone healing (histology and CT), inflammation (histology)

Efficacy evaluation of biodegradable dermal thread /  filler

We evaluate the efficacy and safty of biodegradable dermal thread and filler.

Advantages of biodegradable dermal thread and filler

- the safest materials

- a non-surgical procedure to lift the loose skin and increase the volume of the skin

- collagen synthesis

Analysis : collagen synthesis (histology and western blot), inflammation (histology), wrinkle measurement (replica)

Development of visible biodigradable marker for indication of lesion

We evaluate the visibility and safty of biodegradable marker for indication of lesion.

Advantages of biodegradable marker

- exclusive marker for indication of lesion (existing marker : surgical clip with needle for biopsy )

- avoiding a second surgery for removal

- price competitiveness

- good biocompatibility

Analysis : visibility (X-ray,MRI, ultrasound), inflammation (histology)